The Danger of Heart Damage Associated with Certain Breast Cancer Drugs
Anthracyclines are a commonly used category of chemotherapy drugs for treating breast cancer in women. The best-known drug in this category is Adriamycin. The problem with using these drugs, however, is that they can significantly increase the risk of heart muscle damage.
These drugs work by targeting an Her2 gene contained in many breast cancer tumors. Dr. Dennis Slamon of UCLA’s Jonsson Cancer Center has noted multiple studies which indicate that only about 8-20 percent of cancer patients have an overactive Her2 gene which is sensitive to anthracyclines. When anthracyclines are used in combination with another powerful chemotherapy agent, Herceptin, which also targets Her2 genes in tumors, the risk of heart damage is increased five times with no added therapeutic benefit. For this reason, the National Breast Cancer Coalition is currently suggesting a reconsideration of treatment guidelines.
What constitutes a personal injury?
The most common personal injury is an auto accident, but the broad definition encompasses any situation where a person suffers harm due to the negligence of another person or entity. Early identification of a personal injury is important to the legal process. Many serious injuries occur each year involving:
– Auto accidents
– Premises liability accidents such as injuries caused by a slip and fall
– Medical malpractice/nursing home injuries
– Wrongful death
– Work-related accidents
– Animal attacks
– Faulty or malfunctioning products (product liability)